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«European Journal of Medicine. Series B» – медицинский научный журнал.

ISSN 2409-6296. E-ISSN 2413-7464

Периодичность – 2 раза в год.

Издается с 2014 года.

2 September 29, 2017

1. Orifjon A. Aripov, Liliya R. Sha-Akhmedova, Zakhro A. Usmanova
Evaluation of the Immunological Status and Effectiveness of Therapy in Children with Chronic Virus Hepatitis B

European Journal of Medicine. Series B, 2017, 4(2): 62-70.
DOI: 10.13187/ejm.s.b.2017.2.62CrossRef

There were studied immunological parameters in patients with chronic viral hepatitis B (CVHB) and it was evaluated the effectiveness of flavonoids and phospholipid preparation. There was a decrease in CD3+, CD4+, CD8+ - of lymphocytes, CD4/CD8, CD16+- of cells. The content of CD95 + and TNF-α was significantly increased at all degrees of activity of the cytological process. It was established an increase of the concentration of all types of immunoglobulins (IgA, IgG, IgM) in children. It was established tendency of normalization of the studied parameters in children taking flavonoids, but the level of TNF-α remains high for all therapeutic approaches.

URL: http://ejournal27.com/journals_n/1506685040.pdf
Number of views: 27      Download in PDF

2. Sholpan K. Bakhtiyarova, Unzira N. Kapysheva, Amina K. Baimbetova, Bolat Zhaksymov
The Influence of the Fungus, the Basidiomycete Ganoderma Lucidum for Short-Term Shaped Memory and Performance of People with Dyscirculatory Encephalopathy

European Journal of Medicine. Series B, 2017, 4(2): 71-76.
DOI: 10.13187/ejm.s.b.2017.2.71CrossRef

The use of biologically active food supplements "Ganoderma-Reishi-Lingzhi", developed on the basis of fungus, the basidiomycete Ganoderma Lucidum, improves cognitive functions in people with encephalopaticys disorders of the brain. It is shown that after taking Ganoderma lucidum, an increasing amount of short-term image memory for images, and numbers on average by 5 %, the reduction in visual-motor reaction, the increase in the number of respondents with the performance in the normal range. The average amount of memory for images was increased to 50 %, the amount of memory on the number to 46 %, while before taking Ganoderma Lucidum amount of memorizing images and numbers did not exceed 40 % of the total number of presented stimuli.

URL: http://ejournal27.com/journals_n/1506685120.pdf
Number of views: 19      Download in PDF

3. Oleg V. Gradov
Basic Optical and Corpuscular Physical Principles for Lab-on-a-Chip Constructions with Multiple Non-Optical Physical Signal Conversions into OAS (Optical Analytical Signals) in Multiparametric Experimental Biomedical Engineering Customizations

European Journal of Medicine. Series B, 2017, 4(2): 77-99.
DOI: 10.13187/ejm.s.b.2017.2.77CrossRef

A simplified theory of the optical signal registration using lab-on-a-chip with CMOS/CCD detectors is described. The difference between the contact active and passive chips with optically different possible registration schemes is outlined. For passive chips a possibility of their introduction into a sandwich-like structure with photoelectronic multipliers is also considered (a design of a so-called lab-on-a-PEM similar to the earlier proposed lab-on-a-tube technique where it is possible to integrate the glass surface of the vacuum tube with a microfluidic chip. It is also indicated the possibility of a multiparametric contrastimetry on a chip with a system converting arbitrary physical signals to an optical one. This technique allows to measure contrast, gradient and colocalization of the primary variables (converted signal) distribution in 2D mode with spatial resolution. Either a photoinjection or a photoemission method of estimation of the parameters related to the primary analytical signal for PEM-combined labs-on-a-chip is also proposed. For the simplest “boundary calibration” of the optical CMOS-/CCD-based chip it is suggested to use either white or black balance/level, which after recalculation within a single COBAC system can be applied for estimation of the primary non-optical signal parameters together with contrastimetry. Also an “energy calibration” method is described combining calibration with the photocell and a thermoelement (the parameter measured in this case is specific thermodynamic irradiance). A simple simulation of the light transmission through a biological sample located on a chip to the chip surface was performed using Geant4 software developed by CERN (Scientific Linux OS). The following topology of the on-chip experiment is proposed: a sandwich-type chip system including a light source (LED), emitting photons from the point («World initStep»), a biological cell with cytoplasm («World») and an osmotic vacuole («Tank»), which is a part of the optical path from the light source to the detector of CCD or CMOS chip, which is considered as a target («OutOfWorld») and serves as a substrate for the biological sample. The possibility of the polarization parameter registration at the given experimental scheme and the path geometry is also mentioned. Due to the possibility and the initial application of the Monte-Carlo methods in Geant4 for the nuclear physics, the above model can be extrapolated towards the lab-on-a-chip with either a scintillation primary converter or without it (the operation principle of such a chip is based on the SEU – Single Event Upsets upon the single particle interaction with the pixels). It is also shown that Haar transforms and Fourier registrograms of the line scans from the CCD/CMOS can be considered as one of the sources of visualizable descriptors (both of the optical and primary nonoptical signals).

URL: http://ejournal27.com/journals_n/1506685200.pdf
Number of views: 20      Download in PDF

full number
URL: http://ejournal27.com/journals_n/1506685316.pdf
Number of views: 25      Download in PDF

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